NK-CD11C+ CELL CROSSTALK IN DIABETES ENHANCES IL-6-MEDIATED INFLAMMATION DURING MYCOBACTERIUM TUBERCULOSIS INFECTION.

NK-CD11c+ Cell Crosstalk in Diabetes Enhances IL-6-Mediated Inflammation during Mycobacterium tuberculosis Infection.

In this study, we developed a mouse model of type 2 diabetes mellitus (T2DM) using streptozotocin and nicotinamide and identified factors that increase susceptibility of T2DM mice to infection by Mycobacterium tuberculosis (Mtb).All Mtb-infected T2DM mice and 40% of uninfected T2DM mice died within 10 months, whereas all control mice survived.In Mt

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